Showing posts with label asthma. Show all posts
Showing posts with label asthma. Show all posts

Wednesday, June 2, 2010

Severe allergies and celiac disease respond to treatment and didn't come back

This a recent review of celiac disease immunology. I have found that the combination of dopamine and serotonin precursors utilizing the PURSOR protocol has astounding therapeutic capabilities. Dopamine and 5-HT have reciprocal action, the former promotes Th1 and reigns in Th2 and the latter does the contrary. The PURSOR protocol seems to have the ability to restore Th1/Th2 balance. A patient with celiac disease did respond. Interestingly, she presented with life-threatening idiopathic anaphylaxis which not only also had total recovery but has been in remission for more than 10 years. Apparently, celiac and immediate hypersensitivity disorders do coexist.
In simpler words. Immune diseases are divided into allergies and autoimmune. Celiac disease is an autoimmune. Severe allergies lead to allergic disasters (anaphylaxis). This patient had both types of illness, responded to treatment and has never had a recurrence.
Could TH1 and TH2 diseases coexist? Evaluation of asthma incidence in children with coeliac disease, type 1 diabetes, or rheumatoid arthritis: a register study

Tuesday, November 17, 2009

A Wide Specrum of Maladies are Associated with Immune Imbalance

I have a strong belief that the PURSOR protocol can correct the basic imbalance in both the innate and adaptive immune systems. I have compiled a list of just some of the many conditions whose symptoms and signs are directly associated with this imbalance. You can find at this site a new type of bibliography that I have created at the National Library of Medicine. One can retrieve all the references and then select whether you wish to select all the review articles or those articles with free full texts

Many investigators have postulated that were we to correct this underlying imbalance, commonly referred to as biased Th1/Th2 cytokine dysregulation, the chance of a remission would be likely I offer here two relevant and well-written articles. Moss, R.B. et al (2004) and Lucey, Clerici, & Shearer (1996).

Monday, October 19, 2009

Introduction to Immune disorders and their treatment with PURSOR

GLOSSARY



In my opinion, the neurotransmitters dopamine (DA) and serotonin (5-HT) are the primary regulators of life. These two similar substances control in a reciprocal fashion not only human beings but also all other animal species. More than two millennia ago both the Chinese and the Greeks recognized that "balance is health; imbalance is illness and pain." In summary, DA greatly resembles the Yang and 5-HT the Yin. Western medicine started to recognize this antipodal action in 1957.

Multiple articles in the current medical literature discuss imbalance in the T helper cells. T helper cells are simplistically divided into two major divisions, Th1 and Th2 cells. Harvard's Dr. Kimball summarizes this far better than I can. I would strongly recommend this link. Let's focus on the two major components.
  • The cellular immune system (Th1 driven, Th2 opposes) (increased by DA, suppressed by 5-HT) goes to work when it senses a foreign cell threatening our well-being. These foreign cells can arise from the outside, from viruses and bacteria whose survival inside our body is at the expense of our health or even our survival. This cellular system can also be activated to fight our own cells that have mutated and threaten us with cancer and similar diseases.
  • The humoral system (Th2 driven, Th1 opposes) (increased by 5-HT, suppressed by DA)   becomes activated when it senses that there are foreign proteins threatening to overwhelm us. The humoral system produce antibodies that can safely engulf these foreign chemicals and dispose of them safely.
Interestingly enough, each system controls the other. The cellular system reins in the humoral and the humoral keeps the cellular in control. Th1 suppresses Th2 and Th2 suppresses Th1

Unfortunately, when we are diseased, one or the other system can break out of control and start to overact. If the cellular system excessively dominates, doing its job too well, It starts to attack our own good cells and autoimmune diseases such as lupus, rheumatoid arthritis, psoriasis and Lyme disease ravage our bodies. In the brain, the cellular system running amok can cause neurodegenerative conditions such as Lou Gehrig/s disease or multiple sclerosis that rot our brain and spinal cord.. This is Th1 excess.

Th2 excess conditions, when the humoral system is too vigilant and the body reacts to unimportant levels of foreign protein, are allergic in nature. Asthma, allergic shock, hives and food allergies can cause us woe.Th2 excess.

By the year 2002 there had been already 200 patent applications to bring such imbalances under control. Those folks were looking to create a harmonious equality of the humoral and cellular immune systems or, in fancy terms, a Th1/Th2 balance. The treatments covered in these patent applications shared, in most cases, three qualities. They were toxic, expensive, and ineffectual.

Fortunately, It is apparent when one reads the medical literature that brain dopamine and serotonin controls the Th1/Th2 ratio and can restore it to balance.

  • Dopamine increases TH1 and controls Th2 
  • Serotonin increases Th2 and diminishes Th1. 
Why not, you may ask, don't we correct the Th1/Th2 imbalance and remit illness by increasing the brain levels of dopamine and serotonin?

The administration of the PURSOR protocol which permits our own brain to bring dopamine and serotonin into balance permits us to control either immune system that is overeager and bring us into balance. It is not surprising that when we bring the Th1 and Th2 under control that autoimmune, neurodegenerative, and allergic conditions can remit and stay away as long as the treatment is given.

Immunodeficient conditions are a bit, just a bit, more complicated. In such conditions both the cellular and humoral systems are damaged. I believe, however, with the restoration of proper dopamine and serotonin levels, these conditions  will also improve. I have seen a phenomenal success with an AIDS patient, but that is another story.

Technical section below. Click on title to get full text.

The Restoration of ImmuneTh1/Th2 Balance with Combined Dopamine and Serotonin Agonists

Pietr Hitzig, M.D.
phitz96@gmail.com 

443 231-6240